Stem Cell Therapy in Nashville

June 15, 2026

As Tennessee’s capital and the seat of Davidson County, Nashville anchors one of the largest medical economies in the Southeast, and that scale shapes the stem cell market here. With a population of roughly 715,388 as of 2024 (U.S. Census Bureau), the metro supports everything from hospital-affiliated orthopedic surgeons to independent wellness studios, and the regenerative offerings span a similarly wide range. Most are advertised by regenerative medicine and orthopedic practices, usually under a physician (M.D. or D.O.) or another licensed clinician, who promote injection-based treatments for joint pain, sports injuries, and general wellness. A number of these same offices also provide platelet-rich plasma (PRP), which is a separate procedure built from a concentrate of the patient’s own blood. The breadth of choice along the Cumberland River corridor makes it all the more useful to weigh the marketing against a more cautious regulatory and evidence record.

That record begins with the evidence itself. For the great majority of conditions these injections are pitched to treat, effectiveness has not been established, and clinics frequently bill them as cash-pay services that insurance will not reimburse. PRP sits in a somewhat different and more accepted category because it relies on the patient’s own blood instead of a manufactured stem cell product, yet even there the published research differs sharply from one condition to the next, and a result demonstrated for a single use cannot be assumed to carry over to another. Whatever a practice claims about how well its treatments work is best read as that practice’s own advertising rather than as a settled medical finding. A reader comparing options should press the provider to name the exact product and its FDA or regulatory status, to show the clinical evidence for that reader’s own condition, and to spell out the clinician’s credentials, the total cost, and the risks, then take all of it to a personal physician.

The regulatory side is where the cautions become concrete. The U.S. Food and Drug Administration has approved only certain hematopoietic, or blood-forming, stem cell products derived from cord blood, and only for patients with disorders affecting blood production, a use rooted largely in transplant medicine; the agency states plainly that these products are not approved for anything else. By that standard, the stem cell or “regenerative” injections routinely marketed for arthritis, joint and back pain, sports injuries, anti-aging, or other chronic complaints are generally not FDA-approved for those purposes. The agency has issued repeated consumer warnings about unapproved products, has documented serious adverse events tied to them, among them infections, tumor formation, and vision loss, and has pursued enforcement against both clinics and manufacturers. A 2024 federal court decision upheld the FDA’s authority to regulate unproven stem cell therapies, and in October 2025 the U.S. Supreme Court declined to revisit that ruling.

Oversight in Tennessee runs through the state Department of Health. Physicians who perform these procedures are licensed and regulated by its Board of Medical Examiners, which sets practice standards and also supervises medical spas and office-based surgery settings, and consumers can verify a clinician’s active license and any disciplinary history through the public Tennessee Health Related Boards system before booking. Deceptive or misleading trade practices, which can include unsupported effectiveness claims, fall under the Tennessee Consumer Protection Act (TCA 47-18-104) and the Division of Consumer Affairs. The profiles that follow describe the services each Nashville-area practice markets and attribute any benefit claims to the clinic itself, read alongside the cautions above. This article is informational and is not medical advice.

Top Stem Cell Therapy Providers in Nashville

1. Daniel Hagaman, M.D. (Advanced Ortho & Spine)

Address: 5651 Frist Boulevard, Suite 200, Hermitage, TN 37076
Phone: (615) 885-0200
Website: https://www.danielhagamanmd.com
Services: platelet-rich plasma (PRP) injections, bone marrow aspirate concentrate (BMAC), orthobiologics for knee, hip, and shoulder, regenerative medicine for sports injuries, general orthopedic and sports medicine, arthroscopic surgery
Description: Daniel Hagaman, M.D., is a fellowship-trained orthopedic sports medicine surgeon who practices through Advanced Ortho & Spine, with the Hermitage office listed above (within Metro Nashville-Davidson County) and an additional office in Mt. Juliet at 121 Bear Crossing, Suite 300. His training background includes Vanderbilt University, East Tennessee State University, and the University of Missouri-Kansas City, and his listed professional memberships include the American Academy of Orthopaedic Surgeons, the American Medical Association, and the Tennessee Medical Association. The practice markets PRP and bone marrow aspirate concentrate as non-surgical options, describing BMAC as “a concentrate of regenerative stem cells obtained from your own bone marrow.” As with all such offerings, prospective patients should ask which specific product is used, its regulatory status, and the evidence for their condition, and should note that bone marrow and similar regenerative injections are generally not FDA-approved for orthopedic uses.

2. MaxWell Clinic

Address: 103 Continental Place, Suite 300, Brentwood, TN 37027
Phone: (615) 370-0091
Website: https://maxwellclinic.com
Services: prolotherapy, platelet-rich plasma (PRP), structural tissue products, regenerative injection therapy, IV therapies, hyperbaric oxygen therapy, advanced diagnostics
Description: MaxWell Clinic is an integrative and regenerative medicine practice in Brentwood, in the Nashville metro area immediately south of the city, whose regenerative injection services are associated with Scott Stoll, M.D., FABPMR, described by the clinic as board certified in sports and regenerative musculoskeletal medicine. The clinic offers prolotherapy, PRP, and structural tissue products alongside a broader menu of integrative therapies. In its marketing, the practice describes regenerative medicine as working “to enhance the body’s natural healing mechanisms” and states that “research has demonstrated healing for acute and chronic tendon, ligament, and cartilage injuries,” including conditions such as torn meniscus, plantar fasciitis, and tennis elbow. Those statements are the clinic’s own representations; published evidence varies by condition and procedure, and these treatments are generally not FDA-approved for the advertised musculoskeletal uses, so patients should request the specific supporting data for their situation.

3. Regenerative Solutions Sports and Orthopedics (Ethan Kellum, M.D.)

Address: 125 Cool Springs Boulevard, Suite 240, Franklin, TN 37067
Phone: (615) 850-4415
Website: https://drethankellum.com
Services: stem cell therapy, platelet-rich plasma (PRP), bone marrow aspirate concentrate (BMAC), exosome therapy, alpha-2-macroglobulin (A2M) injections, prolotherapy, regenerative orthopedic treatment for joints, spine, and soft tissue
Description: Regenerative Solutions Sports and Orthopedics, the practice of Ethan Kellum, M.D., a fellowship-trained orthopedic surgeon and sports medicine specialist, operates from Franklin in the southern Nashville metro and serves patients from across the region (the practice was formerly marketed as Nashville Regenerative Orthopedics, and its older web address now redirects to the current site). It markets image-guided regenerative procedures including stem cell therapy, PRP, bone marrow aspirate concentrate, exosome therapy, and A2M injections as non-surgical alternatives to procedures such as joint replacement and spinal fusion. Those are the practice’s own representations rather than independent confirmation of effectiveness; the underlying stem cell and related injections are generally not FDA-approved for the orthopedic uses advertised, and published evidence varies by procedure and condition, so prospective patients should ask about the specific product, its regulatory status, the evidence for their condition, the cost, and the risks, and consult their own physician.

Frequently Asked Questions About Stem Cell Therapy in Nashville

Q: Are the stem cell injections offered by Nashville clinics FDA-approved?

Generally, no. According to the FDA, the only approved stem cell products are certain hematopoietic (blood-forming) products derived from cord blood, approved for blood-production disorders mainly in transplant medicine. Stem cell or “regenerative” injections marketed for arthritis, joint pain, sports injuries, or anti-aging are generally not FDA-approved for those uses. Ask any clinic to identify the exact product and its regulatory status in writing.

Q: How is PRP different from stem cell therapy?

Platelet-rich plasma (PRP) is prepared from a concentrate of the patient’s own blood and is a distinct, more widely accepted procedure than manufactured stem cell products. Even so, the published evidence for PRP varies by condition, and a benefit shown for one use does not mean it works for another. Clinics in Nashville frequently offer both PRP and stem cell injections, so it is worth clarifying which one is being recommended and why.

Q: Does my insurance cover stem cell therapy in Nashville?

Most stem cell and many regenerative injection services are offered as cash-pay treatments and are not covered by insurance, in part because they are not FDA-approved for the advertised uses. Ask for the total cost in writing, including any imaging, follow-up visits, and repeat treatments, before agreeing to a procedure.

Q: How can I check a Nashville provider’s credentials?

Physicians who perform these procedures are licensed by the Tennessee Department of Health through the Board of Medical Examiners. You can confirm a clinician’s active license status and any disciplinary history using the public license verification system maintained by the Tennessee Health Related Boards. Confirming who actually performs the injection, and that person’s credentials, is a reasonable step before treatment.

Q: What questions should I ask before agreeing to a stem cell or PRP procedure?

Ask for the specific product and its FDA or regulatory status, the clinical evidence supporting it for your particular condition, the clinician’s medical credentials, the complete cost, and the risks and possible side effects. The FDA has reported serious adverse events tied to unapproved stem cell products, including infection, tumor formation, and vision loss, so a candid discussion of risk is essential. Most importantly, consult your own physician before deciding.

Q: Where do I report a misleading claim or a dispute with a Nashville clinic?

Complaints about deceptive or misleading trade practices, which can include unsupported claims about how well a treatment works, can be filed with the Tennessee Division of Consumer Affairs under the Tennessee Consumer Protection Act (TCA 47-18-104). Concerns about a physician’s conduct or licensing can be directed to the Tennessee Department of Health Board of Medical Examiners. This article is informational only and is not medical advice; decisions about treatment should be made with a qualified physician.